As a player who's  been paid to play '68 through the present I've owned a 
bunch of amps.   The amp that I gigged with that had the the biggest power was a silver face twin with JBLs (80lbs). I had to take it once to a gig in a taxi cab and decided I needed a better plan.
At this point I've got three rigs: a 22 watt Mesa, 40 watt Fender and 60 watt Tech 21.
My experience has taught me:  
Simpler (smaller wattage) circuits (generally) have better sound
More paper more than more power gives you more sound ('nuff "mores" for ya)
If you can't put the amp in one hand the guitar in the other and walk a block with it - it's an amp that should belong to someone else! 
 
 
Oh yeah, also, keyboard guys who insist on having a B3 with a couple of 122s instead of a Nord Electro or something, are to be avoided like an ex wife with a loaded pistol or a drummer with roto toms.